Regioselective Functionalization of 2-Pyridones through C-H Bond Activation
نویسندگان
چکیده
منابع مشابه
Regioselective syntheses of fully-substituted 1,2,3-triazoles: the CuAAC/C-H bond functionalization nexus.
Regioselective syntheses of 1,4,5-trisubstituted 1,2,3-triazoles were accomplished by three different strategies, relying on (i) the interception of stoichiometrically formed 5-cuprated-1,2,3-triazoles, (ii) the use of stoichiometrically functionalized alkynes or (iii) catalytic C-H bond functionalizations. This perspective article summarizes progress in this research area until June 2010.
متن کاملMild aerobic oxidative palladium (II) catalyzed C-H bond functionalization: regioselective and switchable C-H alkenylation and annulation of pyrroles.
A palladium catalyzed C-H bond functionalization system that operates under ambient and aerobic conditions can be used to alkenylate pyrroles with control of regioselectivty. A steric and electronic control strategy can be used to influence positional control in the C-H bond functionalization process that results in either the C2 or C3 alkenylated products. Air, molecular oxygen, or tBuOOBz can...
متن کاملCarbon–hydrogen (C–H) bond activation at PdIV: a Frontier in C–H functionalization catalysis
The direct functionalization of carbon-hydrogen (C-H) bonds has emerged as a versatile strategy for the synthesis and derivatization of organic molecules. Among the methods for C-H bond activation, catalytic processes that utilize a PdII/PdIV redox cycle are increasingly common. The C-H activation step in most of these catalytic cycles is thought to occur at a PdII centre. However, a number of ...
متن کاملRegioselective Annulation of Aryl Sulfonamides with Allenes through Cobalt-Promoted C-H Functionalization.
The development of an efficient method for the construction of biologically relevant sultams is described, which represents the first case of cobalt-promoted C-H/N-H functionalization of sulfonamides with allenes. This newly developed annulation reaction demonstrated good functional group tolerance and excellent regioselectivity. Both terminal monosubstituted allenes and internal disubstituted ...
متن کاملC–H Functionalization/activation in organic synthesis
The last decade has seen an explosion in research reports in the area of C–H functionalization/activation in organic synthesis. This is not surprising. What is surprising is that it took many in the synthetic organic community this long to fully embrace this exciting and enabling technology. After all, organic compounds mainly consist of a carbon skeleton that bears a large number of hydrogens....
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Synthetic Organic Chemistry, Japan
سال: 2015
ISSN: 0037-9980,1883-6526
DOI: 10.5059/yukigoseikyokaishi.73.753